Exposure to PFOA and PFOS and fetal growth: a critical merging of toxicological and epidemiological data

Year: 2017 • Category: Scientific articles • Language: English
Authors: Eva Negri, Francesca Metruccio, Valentina Guercio, Luca Tosti, Emilio Benfenati, Rossella Bonzi, Carlo La Vecchia, Angelo Moretto

Toxicological and epidemiological evidence on the association between perfluorooctanoic acid (PFOA) or perfluorooctane sulfonic acid (PFOS) and birth/fetal weight was assessed. An extensive search for toxicological information in rats and mice, and a systematic search for epidemiological evidence were conducted.…

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Compilation of a database, specific for the pesticide active substance and their metabolites, comprising the main genotoxicity endpoints

Year: 2017 • Category: Scientific articles • Language: English
Authors: Francesca Metruccio, Ilaria Castelli, Consuelo Civitella, Carmen Galbusera, Francesco Galimberti, Luca Tosti, Angelo Moretto

The terminal residues of pesticide active substances in food and feed commodities need to be duly identified following the requirements of Commission Regulation (EU) No 283/2013 in accordance with Regulation (EC) No 1107/2009. This information is necessary to derive the…

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Toxicological data analysis to support grouping of pesticide active substances for cumulative risk assessment of effects on liver, on the nervous system and on reproduction and development.

Year: 2017 • Category: Scientific articles • Language: Inglese
Authors: Wolterink, G., van Kesteren, P., Mahieu, K., van de Ven, B., Ossendorp, B., Ruggeri, L., Tosti, L., Metruccio, F., Schlitt, C., Moretto, A., Printemps, N., Gouze, M., Charles, S., Angeli, K., Fastier, A., Mercier, T.

EFSA Support. Publ. 10. https://doi.org/10.2903/sp.efsa.2013.en-392

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Toxicological data collection and analysis to support grouping of pesticide active substances for cumulative risk assessment of effects on the nervous system, liver, adrenal, eye, reproduction and development and thyroid system

Year: 2016 • Category: Scientific articles • Language: English
Authors: Gerrit Wolterink, Karin Mahieu, Petra van Kesteren, Coen Graven, Francesca Metruccio, Luca Tosti, Carmen Galbusera, Francesco Galimberti, Karine Angeli, Sabrina Auvray, Sandrine Charles, Juliette Jobard, Antony Fastier, Marie-Estelle Gouze, Géraldine Klegou, Thierry Mercier, Nathalie Printemps

EFSA and the PPR Panel have started in 2007 the development of methodologies to carry out cumulative risk assessment for Maximum Residue Levels setting which implies the establishment of cumulative assessment groups (CAGs) of pesticidal active substances on the basis…

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